Ascorbate anion potentiates cytotoxicity of nitro-aromatic compounds under hypoxic and anoxic conditions
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چکیده
منابع مشابه
Degradation of aromatic compounds in plants grown under aseptic conditions.
The aim of the work is to investigate the ability of higher plants to absorb and detoxify environmental pollutants - aromatic compounds via aromatic ring cleavage. Transformation of 14C specifically labelled benzene derivatives, [1-6-14C]-nitrobenzene, [1-6-(14)C]-aniline, [1-(14)C]- and [7-(14)C]-benzoic acid, in axenic seedlings of maize (Zea mays L.), kidney bean (Phaseolus vulgaris L.), pea...
متن کاملMelamine trisulfonic acid catalyzed regioselective nitration of aromatic compounds under solvent-free conditions
A simple, mild and efficient method for the regioselective nitration of various aromatic compounds usingpoly(4-vinylpyridinium nitrate) (P4VPyN) in the presence of melamine trisulfonic acid (MTSA), is reported.This method provides several advantages such as good selectiveity between ortho and para positions ofaromatic compounds, clean procedure, simple work-up, short reaction times, solvent-fre...
متن کاملOne-pot efficient reductive acetylation of aromatic nitro compounds
An efficient one-pot reductive acetylation of aromatic nitro compounds is developed without isolating the intermediate amine. The nitro compound is efficiently reduced by sodium borohydride and catalytic amount of Pd-C in MeOH-water media in presence / absence of alkali, and the amine thus generated is acetylated by acetic anhydride in situ in excellent yields through easy work-up. The techniqu...
متن کاملBiotransformation of Nitro Aromatic Compounds by Flavin-Free NADH-Azoreductase
Nitro aromatic compounds are the potential toxic organic pollutant released into the environment and are often resistant to degradation under normal environmental conditions. The biotransformation and/or detoxification of these compounds can be possible by microbial azoreductase enzyme. Azoreductase enzyme has an ability to reduce the toxic nitro group to corresponding amino group. In present r...
متن کامل[Reduction of aromatic nitro compounds in the intestine].
An ortho-nitrophenol solution was injected into the intestine which had been removed from an anesthetized mouse by placing a ligature at the duodenum and at the rectum. The intestine was then incubated in Ringer's solution at 37•Ž and the ortho-nitrophenol was found to be reduced to ortho aminophenol. At the same time, it was found that ortho-nitrophenol which was incubated with the intestinal ...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1979
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1979.56